Dr Joanne Pennock

Joanne Pennock – Research summary

Dr Joanne Pennock

Dr Joanne Pennock

The focus of our lab is the study of gut inflammation, its induction, resolution and treatment from an immunology perspective. We use models of helminth infection to inform clinical research. Our work impacts on the understanding of soil transmitted worm infection, and the ill-health that it causes worldwide. However, studying colonic inflammation in this way also impacts on our understanding of conditions such as Crohn’s disease. We have demonstrated that chronic nematode infection induces Crohn’s-like pathology in the colon (Levison et al. 2010), allowing us to manipulate worm infection models to study both disease induction and genetic susceptibility to gut inflammation (Levison et al. 2013). We are interested in the role of the nervous system in the initiation and susceptibility to both large and small intestinal inflammation, with particular emphasis on the cross talk at mucosal surfaces between various nerve subtypes and the immune response. We have collaborations with clinicians in the gastrointestinal and dermatological fields, which allow rapid application of lab findings to clinical research and observations.

Email: joanne.pennock@manchester.ac.uk | Tel: 0161 275 5133 | Twitter: @immunojo

People

Joanne Pennock – People

Mushref Bakri Assas (Postdoc)
Abdullah Alkahtahi (PhD student)
Basmah ElDakhakhny (PhD Student)
Vicky Bridge (PhD Student)
Maryam Moradi (Technician)

Previous lab group members

Swapna Vaddi
Scott Levison
Soo Yee Tan

People

Joanne Pennock – People

Mushref Bakri Assas (Postdoc)
Abdullah Alkahtahi (PhD student)
Basmah ElDakhakhny (PhD Student)
Vicky Bridge (PhD Student)
Maryam Moradi (Technician)

Previous lab group members

Swapna Vaddi
Scott Levison
Soo Yee Tan

Collaborators

Dr Peter Arkwright, Royal Manchester Children's Hospital, Manchester.
Dr Scott Levison, Manchester Royal Infirmary, Manchester.
Dr John McLaughlin, Senior Lecturer/Honorary Consultant Gastroenterologist, School of Translational Medicine.
Dr Jaleel Miyan, Senior Lecturer, Faculty of Biology, Medicine and Health.

Biography

I am a non-clinical lecturer in the School of Biological Sciences, Faculty of Biology, Medicine and Health.

I was first appointed as a lecturer in the Faculty of Medicine and Human Sciences in 2007. I am the postgraduate trainer for The Institute of Inflammation and Repair, and the academic lead for the Clinical Immunology pathway of the NHS driven Modernising Scientific Careers program; this professional qualification provides practical and academic training for the next generation of clinical immunologists. I am also heavily involved in public engagement activities, both independently and under the auspices of the Worm Wagon. I love creating resources which engage the public in a dialogue about our research. Output from various events can be found on our Youtube space and Public Activities pages. Together with research colleagues Dr Sheena Cruickshank and Professor Else, I was recently awarded the Women in STEM award by Manchester City Council for our collective work with the Worm Wagon. I also feel passionately about the importance of women in scientific careers, and am one of the Athena Swan Champions for the Institute of Inflammation & Repair.